Publicações | Prof. Dr. Leandro Piovan

38) Souza, J. P. A.; Jacobs, A. K.; Piovan, L.; Campos, R. B. Org. Biomol. Chem. 2024, 22, 3926-3932. (DOI 10.1039/D4OB00160E)

Exploring the mechanism of the reductive amination of acetophenones via the Borch approach: the role of the acid catalyst

37) Aggio, B. B.; de Oliveira, A. R. M.; Piovan, L.*; Thomas, J. C. Rev. Virtual Quim. 2023, 15, 367-373. (DOI 10.21577/1984-6835.20230006)

A Chemoenzymatic Synthesis of Optically Active Mandelic Acid Employing Continuous-Flow Resolution of Cyanohydrin as a Key Step

36) Burich, M. D.; Bandeira, P. T.; de Oliveira, A. R. M.; Piovan, L.; Thomas, J. C. Rev. Virtual Quim. 2023, 15, 213-220. (DOI 10.21577/1984-6835.20220117)

Non-linear Tendency Between Acyl Chain Length and Selectivity in Enzymatic Deacylation of Carboxylic Esters in Batch and Continuous-Flow

35) Zugman, T.; Durigon, M. C. S.; Campos, S. K.; da Silva, R. R.; da Silva, T. S.; de Oliveira, A. R. M.; Piovan, L.* ChemistrySelect 2022, 7, e2022038. (DOI 10.1002/slct.202203883).

Exquisite use of Selenoesters as Recyclable Acyl Donors for Lipases-catalyzes kinetic resolution

34) Gomes, J. S. O.; da Silva, M. E.; Reis, J. S.; Piovan, L.*; Thomas, J. C. 2023, 4, 100603. (DOI 10.1016/j.rechem.2022.100603)

Brazilian contributions to Alcohol dehydrogenases-catalyzed reactions throughout the 21st century

33) Burich, M. D.; Bandeira. P. T.; de Oliveira, A. R. M.; Piovan, L.*; Thomas, J. C. Rev. Virtual Quim. 2023, aceito. (DOI 10.21577/1984-6835.2022011)

Non-linear Tendency Between Acyl Chain Length and Selectivity in Enzymatic Deacylation of Carboxylic Esters in Batch and Continuous-Flow

32) Souza, J. P. A.; Bandeira, P. T.; Menezes, L. R. A.; Bespalhok, M. B.; Scariot, D. B.; Garcia, F. P.; Giese, S. O. K.; Hughes, D. L.; Nakamura, C. V; Barison, A.; Oliveira, A. R. M.; Campos, R. B.; Piovan, L.* Chem. Eur. J. 2021, 14427-14437. (DOI10.1002/chem.202102287).

Synthesis, Mechanism Elucidation and Biological Insights of Tellurium(IV)-containing Heterocycles

31) Bom, M. A. T.; Botton, V.; Altheia, F. M.; Thomas. J. C.; Piovan, L.; Córdova, J.; Mitchell, D. A.; Krieger, N. Biochem. Eng. J. 2021, 165, 107817. (DOI 10.1016/j.bej.2020.107817)

30) Borges, F. G.; Zugman, T.; Bandeira, P. T.; Dalmolin, M. C.; Scariot, D. B.; Garcia, F. P.; de Oliveira, A. R. M.; Nakamura, C. V.; Piovan, L.* J. Braz. Chem. Soc. 2021, 32, 462-475. (DOI 10.21577/0103-5053.20200201)

Complementary Performance of Organoselenides and Organotellurides as Antimicrobials Agents

29) Bandeira, P. T.; Gotor-Fernández, V.; Piovan, L.* Eur. J. Org. Chem. 2020, 1129-1135. (DOI 10.1002/ejoc.201901841)

Stereoselective Bioreduction of Telluro-acetophenones to Optically Active Hydroxy Tellurides

28) Dias, G. S.; Bandeira, P. T.; Jaerger, S.; Piovan, L.; Mitchell, D. A.; Wypych, F.; Krieger, N. Enzyme Microb. Tech. 2019, 130, 109365.

Immobilization of Pseudomonas cepacia lipase on layered double hydroxide of Zn/Al-Cl for kinetic resolution of rac-1-phenylethanol

27) Barros, H. R.; Santos, M. C.; Barbisa, L. R. S.; Piovan, L.; Riegel-Vidotti, I. C. J. Braz. Chem. Soc. 2019, 00, 1-12. (DOI 10.21577/0103-5053.20190127)

Physicochemical Study of the Interaction between Gold Nanoparticles and Lipase from Candida sp. (CALB): Insights into the Nano-Bio Interface

26) Thomas, J. C.; Alnoch, R. C.; Costa, A. C. S.; Bandeira, P. T.; Burich, M. D.; Campos, S. K.; de Oliveira, A. R. M.; de Souza, E. M.; Pedrosa, F. O.; Krieger, N.; Piovan, L.* Molecular Catalysis 2019, 473, 110402. (DOI 10.1016/j.mcat.2019.110402)

LipG9-mediated enzymatic kinetic resolution of racemates: expanding the substrate-scope for a metagenomic lipase

25) Bandeira, P. T.; Souza, J. P. A.; Scariot, D. B.; Garcia, F. P.; Nakamura, C. V.; de Oliveira, A. R. M.; Piovan, L.* ACS Med. Chem. Lett. 2019, 10, 806-810. (DOI 10.1021/acsmedchemlett.9b00060)

Diacetal Ditellurides as Highly Active and Selective Antiparasitic Agents Toward Leishmania amazonensis

24) Bandeira, P. T.; Dalmolin, M. C.; de Oliveira, M. M.; Nunes, K. C.; Garcia, F. P.; Nakamura, C. V.; de Oliveira, A. R. M.; Piovan, L.* Bioorg. Med. Chem. 2019, 27, 410-415. (DOI 10.1016/j.bmc.2018.12.017)

Synthesis, Antioxidant Activity and Cytotoxicity of N-Functionalized Organotellurides

23) Serres, J. D. S.; Bandeira, P. T.; Zappani, P. C.; Piovan, L.; Corazza, M. L. J. Supercrit. Fluids 2019, 143, 330–335. (DOI 10.1016/j.supflu.2018.09.011)

A greener bioreduction using baker’s yeast cells in supercritical carbon dioxide and glycerol system.

22) Dalmolin, M. C.; Bandeira, P. T.; Ferri, M.; de Oliveira, A. R. M.; Piovan, L.* J. Organomet. Chem. 2018, 874, 32-39. (DOI 10.1016/j.jorganchem.2018.08.007)

Straighforward microwave-assisted synthesis of organochalcogen amines by reductive amination.

21) Teixeira, M. L.; Menezes, L. R. A.; Barison, A.; de Oliveira, A. R. M.; Piovan, L.* J. Org. Chem. 2018, 83, 7341-7346. (DOI 10.1021/acs.joc.7b02971)

Investigation of Chemical Stability of Dihalogenated Organotelluranes in Organic−Aqueous Media: The Protagonism of Water

20) Botton, V.; Piovan, L.; Meier, H. F.; Mitchell, D. A.; Cordova, J.; Krieger, N. Bioprocess Biosystems Eng. 2018, 41, 573-583. (DOI 10.1007/s00449-018-1892-5)

Optimization of biodiesel synthesis by esterification using a fermented solid produced by Rhizopus microsporus on sugarcane bagasse.

19) Bandeira, P. T.; Thomas, J.C.; Oliveira, A. R. M.; Piovan, L.* J. Chem. Ed. 2017, 94, 800-805. (DOI 10.1021/acs.jchemed.6b00606)

Lipase-Mediated Kinetic Resolution: An Introductory Approach to Practical Biocatalysis.

18) Thomas, J. C.; Burich, M. D.; Bandeira, P. T.; Oliveira, A. R. M.; Piovan, L.* Biocatalysis 2017, 3, 27- 36. (DOI 10.1515/boca-2017-0003)

Biocatalysis in continuous-flow mode: A case study in the enzymatic kinetic resolution of secondary alcohols via acylation and deacylation reactions mediated by Novozym 435.

17) da Silva, T. S.; Campos, S. K.; Oliveira, A. R. M.; Piovan, L.* J. Mol. Catal. B, Enzymatic 2016, 133, S317–S323. (10.1016/j.molcatb.2017.02.001)

An unexpected inversion of CAL-B enantiopreference based on substrate engineering of 2-bromoesters: Effect of (R)-1-phenylethyl moiety.

16) Thomas, J. C.; Aggio, B. B.; Oliveira, A. R. M.; Piovan, L.* Eur. J. Org. Chem. 2016, 5964–5970. (DOI 10.1002/ejoc.201601028)

High-Throughput Preparation of Optically Active Cyanohydrins Mediated by Lipases.

15) Barros, H. R.; Piovan, L.; Sassaki, G. L.; Sabry, D. A.; Mattoso, N.; Nunes, A. M.; Meneghetti, M. R. Riegel-Vidotti, I. C. Carbohydrate Polymers 2016, 152, 479–486. (DOI 10.1016/j.carbpol.2016.07.018)

Surface interactions of gold nanorods and polysaccharides: From clusters to individual nanoparticles

14) Bandeira, P. T.; Alnoch, R. C.; Oliveira, A. R. M.; Souza, E. M.; Pedrosa, F. O.; Piovan, L.* J. Mol. Catal. B, Enzymatic 2016, 125, 58-63. (j.molcatb.2015.12.010)

Enzymatic kinetic resolution of aliphatic sec-alcohols by LipG9, a metagenomic lipase.

13) de Oliveira, A. R. M.; Piovan, L.; Simonelli, F.; Barison, A.; Santos, M. F. C. de Mello, M. B. M. J. Organomet. Chem. 2016, 806, 54-59. (DOI 10.1016/j.jorganchem.2016.01.028)

A ⁷⁷Se NMR study of elemental selenium reduction using NaBH₄.

12) Alnoch, R. C.; Martini, V. P. ; Costa, A. C. S.; Piovan, L.; Muller-Sanstos, M.; Souza, E. M.; Pedrosa, F. O.; Mitchell, D.; Krieger, N. PLoS One, 2015, 10. (DOI 10.1371/journal.pone.0114945)

Immobilization and Characterization of a New Regioselective and Enantioselective Lipase Obtained from a Metagenomic Library.

11) de Mello, M. B.M.; Clososki, G. C.; Piovan, L.; de Oliveira, A. R.M. J. Organomet. Chem. 2015, 794, 11-16. (DOI 10.1016/j.jorganchem.2015.06.022)

An alternative approach to differentially substituted 2-oxazoline chalcogen derivatives.

10) Piovan, L.; Milani, P.; Silva, M. S.; Moraes, P. G.; Demasi, M.; Andrade, L. H. Eur. J. Med. Chem. 2014, 73, 280-285. (DOI 10.1016/j.ejmech.2013.12.011)

20S proteasome as novel biological target for organochalcogenanes.

9) Madalozzo, A. D.; Muniz, L. S.; Baron, A. M.; Piovan, L.; Mitchell, D. A.; Krieger, N. Biocatalysis and Agricultural Biotechnology 2014, 3, 13-19. (DOI 10.1016/j.bcab.2013.12.005)

Characterization of an immobilized recombinant lipase from Rhizopus oryzae: Synthesis of ethyl-oleate.

8) Piovan, L.; Wu, L.; Zhang, Z.; Andrade, L. H. Org. Biomol. Chem. 2011, 9, 1347-1351. (DOI 10.1039/C0OB01050B)

Hypervalent Organochalcogenanes as Inhibitors of Protein Tyrosine Phosphatases.

7) Piovan, L.; Alves, M. F. M.; Juliano, L.; Bromme, D.; Cunha, R. L. O. R.; Andrade, L. H. Bioorg. Med. Chem. 2011, 19, 2009-2014. (DOI 10.1016/j.bmc.2011.01.054)

Structure-Activity Relationships of Hypervalent Organochalcogenanes as inhibitors of cysteine cathepsins V and S.

6) Piovan, L.; Pasquini, M. D.; Andrade, L. H. Molecules 2011, 16, 8098-8109. (DOI 10.3390/molecules16098098)

Enzymatic Kinetic Resolution of tert-Butyl 2-(1-Hydroxyethyl)phenylcarbamate, A Key Intermediate to Chiral Organoselenanes and Organotelluranes.

5) Piovan, L.; Kagohara, E.; Vale, J. A.; Comasseto, J. V.; Shoenlein-Crusius; Andrade, L. H.; Porto, A. L. M. Food Technol. Biotechnol. 2011, 49, 460-464.

Demethylation of N,N-Dimethylbenzenamine and N,N,3-Trimethylbenzenamine by Whole Cells of Aspergillus terreus.

4) Piovan, L.; Alves, M. F. M.; Juliano, L.; Bomme, D.; Cunha, R. L. O. R ; Andrade, L. H. J. Braz. Chem. Soc. 2010, 21, 2108-2118. (DOI 10.1590/S0103-50532010001100012)

Chemoenzymatic synthesis of organoselenium(IV) compounds and their evaluation as cysteine protease inhibitors.

3) Andrade, L. H.; Piovan, L.; Pasquini, M. D. Tetrahedron: Asymm. 2009, 20, 1521-1525. (DOI 10.1016/j.tetasy.2009.05.033)

Improving the enantioselective bioreduction of aromatic ketones mediated by Aspergillus terreus and Rhizopus oryzae: the role of glycerol as a co-solvent.

2) Piovan, L.; Kagohara, E.; Ricci, L. C.; Keppler, A. F.; Andrade, L. H.; Comasseto, J. V.; Porto, A. L. M. Tetrahedron. Asymm. 2008, 19, 2385-2389. (DOI 10.1016/j.tetasy.2008.10.003)

Chemoselective screening for the reduction of a chiral functionalised (±)-2 -(phenylthio)cyclohexanone by whole cells of Brazilian micro-organisms.

1) Piovan, L.; Capelari, M.; Andrade, L. H.; Comasseto, J. V.; Porto, A. L. Tetrahedron: Asymm. 2007, 18, 1398-1402. (DOI 10.1016/j.tetasy.2007.05.036)

Biocatalytic reduction of a racemic selenocyclohexanone by Brazilian basidiomycetes.